Fleming’s discovery - and a warning
In 1928, Alexander Fleming noticed a patch of mould killing bacteria on a petri dish - the birth of penicillin. It transformed medicine: lifesaving in wartime, in childbirth, cancer care, and so much else we now take for granted. Antibiotics also helped bring childhood mortality to historic lows. Before they existed, infections like pneumonia, meningitis, sepsis or even simple ear and throat infections were major causes of childhood deaths. Antibiotics changed that almost overnight.
But even in 1945, Fleming warned that misuse would lead to resistance. 80 years on, infections once easily treated - pneumonia, UTIs and gonorrhoea - are becoming harder to manage. Drug-resistant infections kill 1.25 million people deaths globally each year.
Antibiotics are powerful - but not harmless
We often think of antibiotics as routine and safe, but they can disrupt healthy gut bacteria, causing diarrhoea, and can sometimes allow infections like Clostridioides difficile to take hold.
Some antibiotics also carry very serious side effects, and many can cause common, mild side effects such as stomach upset. It’s important to distinguish these from an allergy, which involves an immune response like a rash, swelling, or breathing difficulty. Confusing the two can lead to unnecessary fear, when a medicine, like penicillin, may actually be the safest, most effective choice. Most coughs, colds, sore throats and flu-like illnesses are viral and get better on their own. The same is true for some dental or ear infections.
Clearing up common misconception
- People don’t become resistant – bacteria do
- Resistant infections don’t only affect those who have taken many antibiotics. Resistant bacteria spread between people and through food, water and the environment
- AMR isn’t only about using fewer antibiotics. It’s about safer, appropriate use
Vaccination helps protect antibiotics
Preventing infections means fewer antimicrobials in the first place. Vaccines make a huge difference by reducing illnesses like flu and COVID-19 and the secondary bacterial infections that can follow. Fewer infections mean fewer antibiotic prescriptions - and fewer chances for resistance to develop.
Keeping up to date with routine vaccinations, including influenza and the MenACWY vaccine for young adults, is one of the simplest ways to protect these medicines.
AMR work in West Yorkshire
- Across West Yorkshire, teams are working together to tackle AMR, including:
- Infection prevention and control specialists preventing outbreaks
- Pharmacists and medicines optimisation teams ensuring people receive the right medicine at the right time
- Laboratory teams identifying resistance
- Public health teams running education campaigns in communities and schools
- Clinicians and care providers across all settings
- Research teams advancing innovation
- Our improving population health AMR fellows, communication and other colleagues all working on this shared challenge
What you can do this awareness week
- Join the campaign
- Only take antibiotics prescribed for you
- Don’t buy unprescribed antibiotics online or abroad
- Return unused antibiotics to your local pharmacy for safe disposal - never keep, share, throw in the bin or flush them away. It protects you, your family and the environment.
- Keep vaccinations up to date and practise good hygiene
- Talk about AMR
AMR may be invisible, but its impact is real. Small actions today can secure a safer future tomorrow.
Find out more:
- Seriously Resistant – our West Yorkshire campaign on using antibiotics wisely
- Antibiotic Guardian – make your personal pledge
- WY ICB NHS AMR animations – short films on preventing infection and reducing antibiotic use
- UKHSA Andi-biotic films
Thank you for reading
Sarah





